Developing a consensus classification system for acute renal failure

Curr Opin Crit Care. 2002 Dec;8(6):509-14. doi: 10.1097/00075198-200212000-00005.


A biochemical definition and classification system for acute renal dysfunction is long overdue. Its absence has impeded progress in clinical and even basic research concerning a syndrome associated with mortality rates of 30 to 80%. No definition of acute renal dysfunction will be perfect, but the absence of a definition or, worse, more than 35 separate definitions, as found in the literature, is unacceptable. Many of the challenges, considerations, and controversies associated with achieving consensus and developing a classification for acute renal dysfunction are addressed. Recommendations for validating a classification system are also considered.

Publication types

  • Review

MeSH terms

  • Acute Kidney Injury / classification*
  • Classification / methods
  • Consensus
  • Humans
  • Kidney Function Tests
  • Sensitivity and Specificity
  • Terminology as Topic
  • Uremia / diagnosis