Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
, 32 Suppl, 490-5

Fundamentals of Experimental Design for cDNA Microarrays

Affiliations
Review

Fundamentals of Experimental Design for cDNA Microarrays

Gary A Churchill. Nat Genet.

Abstract

Microarray technology is now widely available and is being applied to address increasingly complex scientific questions. Consequently, there is a greater demand for statistical assessment of the conclusions drawn from microarray experiments. This review discusses fundamental issues of how to design an experiment to ensure that the resulting data are amenable to statistical analysis. The discussion focuses on two-color spotted cDNA microarrays, but many of the same issues apply to single-color gene-expression assays as well.

Similar articles

See all similar articles

Cited by 258 articles

See all "Cited by" articles

Publication types

Substances

LinkOut - more resources

Feedback