Metric characteristics of the drug-induced extrapyramidal symptoms scale (DIEPSS): a practical combined rating scale for drug-induced movement disorders

Mov Disord. 2002 Nov;17(6):1354-9. doi: 10.1002/mds.10255.


The metric properties of the Drug-Induced Extrapyramidal Symptoms Scale (DIEPSS) were examined in 182 subjects treated with antipsychotics. Inter-rater reliability, test-retest reliability, and concurrent validity with other rating scales for EPS were high. Four factors were identified and the optimal diagnostic cut-off scores were obtained. These results suggest that the DIEPSS is a reliable and valid multidimensional rating scale.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Akathisia, Drug-Induced / diagnosis
  • Antipsychotic Agents / adverse effects*
  • Antipsychotic Agents / therapeutic use
  • Basal Ganglia Diseases / chemically induced*
  • Basal Ganglia Diseases / diagnosis
  • Dyskinesia, Drug-Induced / diagnosis
  • Female
  • Humans
  • Male
  • Middle Aged
  • Neurologic Examination / statistics & numerical data*
  • Observer Variation
  • Parkinsonian Disorders / chemically induced
  • Parkinsonian Disorders / diagnosis
  • Reproducibility of Results
  • Schizophrenia / drug therapy*


  • Antipsychotic Agents