Hereditary chin trembling: a new family with exclusion of the chromosome 9q13-q21 Locus

Mov Disord. 2002 Nov;17(6):1390-2. doi: 10.1002/mds.10275.

Abstract

Hereditary chin trembling is a rare autosomal dominant condition that has been linked to chromosome 9q13-21 in one kindred. We describe a four-generation family with this condition and, using linkage analysis, have excluded the 9q13-21 region as causing the chin trembling in this family.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Botulinum Toxins, Type A / administration & dosage
  • Chin / innervation*
  • Chromosome Mapping*
  • Chromosomes, Human, Pair 9*
  • Female
  • Genetic Linkage
  • Humans
  • Male
  • Middle Aged
  • Pedigree
  • Tremor / diagnosis
  • Tremor / drug therapy
  • Tremor / genetics*

Substances

  • Botulinum Toxins, Type A