Protective effects of trilinolein extracted from panax notoginseng against cardiovascular disease

Acta Pharmacol Sin. 2002 Dec;23(12):1157-62.


Trilinolein is a triacylglycerol purified from a commonly used traditional Chinese medicine Panax notoginseng. Trilinolein has been reported to provide a number of beneficial effects including reducing thrombogenicity and arrhythmias and increasing erythrocyte deformability. Additionally, trilinolein has been reported to be an antioxidant, which can counteract free radical damage associated with atherogenesis, and myocardial damage seen with ischaemia and reperfusion. These pharmacologic effects may explain the perceived benefits derived from treating circulatory disorders with the herb over the centuries.

Publication types

  • Review

MeSH terms

  • Animals
  • Anti-Arrhythmia Agents / therapeutic use
  • Antioxidants / therapeutic use
  • Cardiotonic Agents / therapeutic use*
  • Humans
  • Myocardial Infarction / pathology
  • Myocardial Infarction / prevention & control*
  • Panax / chemistry*
  • Plants, Medicinal / chemistry
  • Platelet Aggregation / drug effects
  • Triglycerides / isolation & purification
  • Triglycerides / therapeutic use*


  • Anti-Arrhythmia Agents
  • Antioxidants
  • Cardiotonic Agents
  • Triglycerides
  • trilinolein