Prevalence of dermatomycoses in Mal de Meleda patients: a field study

Scand J Infect Dis. 2002;34(10):753-5. doi: 10.1080/00365540210147868.

Abstract

Mal de Meleda is a rare autosomal recessive form of palmoplantar keratoderma characterized by hyperkeratosis of the palms and soles. The presence of yeast and dermatophytes was investigated in 29 mal de Meleda patients from Koprucay canyon, Turkey, a newer geographical focus, and was found in 62.0% and 20.7% of cases, respectively. Antifungal resistance of isolates was not detected.

MeSH terms

  • Adult
  • Aged
  • Amphotericin B / pharmacology
  • Antifungal Agents / pharmacology*
  • Biopsy, Needle
  • Comorbidity
  • Dermatomycoses / drug therapy
  • Dermatomycoses / epidemiology*
  • Dermatomycoses / microbiology*
  • Female
  • Fluconazole / pharmacology
  • Follow-Up Studies
  • Humans
  • Itraconazole / pharmacology
  • Keratoderma, Palmoplantar / epidemiology*
  • Keratoderma, Palmoplantar / genetics
  • Keratoderma, Palmoplantar / microbiology*
  • Male
  • Microbial Sensitivity Tests
  • Middle Aged
  • Prevalence
  • Prospective Studies
  • Risk Assessment
  • Sampling Studies
  • Skin / microbiology
  • Skin / pathology
  • Treatment Outcome
  • Turkey / epidemiology

Substances

  • Antifungal Agents
  • Itraconazole
  • Amphotericin B
  • Fluconazole