Cytokinesis: rho and formins are the ringleaders

Curr Biol. 2002 Dec 10;12(23):R813-4. doi: 10.1016/s0960-9822(02)01316-7.

Abstract

Although cytokinesis was first described in the 1830s, the molecular events underlying this key cellular process remain elusive. New results reveal a role for actin polymerization, the small GTPase Rho and formins in cytokinetic ring assembly.

Publication types

  • Review
  • Comment

MeSH terms

  • Actomyosin / physiology
  • Animals
  • Cell Division / physiology*
  • Schizosaccharomyces / cytology
  • Schizosaccharomyces / physiology
  • rho GTP-Binding Proteins / metabolism*

Substances

  • Actomyosin
  • rho GTP-Binding Proteins