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. 2003 Jan 1;312(1):57-65.
doi: 10.1016/s0003-2697(02)00431-1.

Analysis of Exponential Data Using a Noniterative Technique: Application to Surface Plasmon Experiments

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Analysis of Exponential Data Using a Noniterative Technique: Application to Surface Plasmon Experiments

Raimund J Ober et al. Anal Biochem. .

Abstract

The analysis of experimental data of exponential type plays a central role in many biophysical applications. We introduce a novel noniterative algorithm to analyze the association phase and dissociation phase of surface plasmon resonance experiments. It is shown that this algorithm can determine kinetic constants with a high level of accuracy in the presence of significant levels of noise. This algorithm should provide a valuable alternative to existing data analysis techniques.

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