Biochemical and molecular mechanisms of cisplatin resistance

Cancer Treat Res. 2002;112:263-84. doi: 10.1007/978-1-4615-1173-1_13.
No abstract available

Publication types

  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Antineoplastic Agents / therapeutic use*
  • Cisplatin / therapeutic use*
  • DNA / metabolism
  • DNA Damage
  • DNA Repair
  • Drug Resistance, Neoplasm*
  • Glutathione / metabolism
  • Humans
  • Proto-Oncogene Proteins c-bcl-2 / metabolism
  • Sulfhydryl Compounds
  • Tumor Suppressor Protein p53 / metabolism

Substances

  • Antineoplastic Agents
  • Proto-Oncogene Proteins c-bcl-2
  • Sulfhydryl Compounds
  • Tumor Suppressor Protein p53
  • DNA
  • Glutathione
  • Cisplatin