Abstract
We report the case of a 56-yr-old woman with adenocarcinoma of unknown origin metastatic to the bone marrow presenting with a thrombotic thrombocytopenic purpura-like syndrome refractory to protracted daily plasmapheresis and steroids but readily and completely responsive to docetaxel plus cisplatin. Sustained and complete response was pathologically confirmed.
MeSH terms
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Adenocarcinoma / drug therapy
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Adenocarcinoma / secondary
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Anemia, Hemolytic / etiology
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Anemia, Hemolytic / therapy*
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Anti-Inflammatory Agents, Non-Steroidal / therapeutic use
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Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
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Bone Neoplasms / drug therapy
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Bone Neoplasms / secondary
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Cisplatin / administration & dosage
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Cisplatin / therapeutic use*
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Docetaxel
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Female
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Hemolysis
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Humans
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Methylprednisolone / therapeutic use
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Middle Aged
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Paclitaxel / administration & dosage
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Paclitaxel / analogs & derivatives*
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Paclitaxel / therapeutic use*
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Plasmapheresis
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Taxoids*
Substances
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Anti-Inflammatory Agents, Non-Steroidal
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Taxoids
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Docetaxel
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Paclitaxel
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Cisplatin
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Methylprednisolone