Translocation of Broca's area to the contralateral hemisphere as the result of the growth of a left inferior frontal glioma

J Comput Assist Tomogr. Nov-Dec 2002;26(6):941-3. doi: 10.1097/00004728-200211000-00014.


We report a case of a patient with a left inferior frontal glioma in whom language functional magnetic resonance imaging (fMRI) paradigms produced activation of Broca's area on the right and Wernicke's area on the left. We propose that tumor invasion of the left frontal operculum led to cortical reorganization and interhemispheric transfer of Broca's area. This case emphasizes the importance of preoperative fMRI in assessing the location of eloquent cortices adjacent to a tumor and in guiding neurosurgical decision-making.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Brain Neoplasms / complications*
  • Brain Neoplasms / surgery
  • Decision Making
  • Frontal Lobe / abnormalities
  • Frontal Lobe / physiology*
  • Functional Laterality
  • Glioma / complications*
  • Glioma / surgery
  • Humans
  • Language*
  • Magnetic Resonance Imaging
  • Male
  • Neurosurgical Procedures
  • Postoperative Complications / prevention & control*
  • Temporal Lobe / abnormalities
  • Temporal Lobe / physiology*