A case of systemic lupus erythematosus that manifested in the course of schizophrenia

Scand J Rheumatol. 2002;31(6):374-6. doi: 10.1080/030097402320817121.

Abstract

A case of schizophrenia is presented in which SLE was diagnosed after 14-year duration. Antibodies to single and double-stranded DNAs, but not to histone. were detected. This case suggests that similar immunological abnormalities as SLE are associated with the pathogenesis of a group of schizophrenia and that class-switch of anti-dsDNA antibodies are important in the pathogenesis of SLE.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Antibodies, Antinuclear / analysis
  • Antibodies, Antinuclear / biosynthesis
  • Antibodies, Antinuclear / immunology*
  • Disease Progression
  • Female
  • Humans
  • Lupus Erythematosus, Systemic / etiology
  • Lupus Erythematosus, Systemic / immunology*
  • Lupus Erythematosus, Systemic / pathology
  • Schizophrenia / immunology
  • Schizophrenia / physiopathology*

Substances

  • Antibodies, Antinuclear