Anti-inflammatory, antipyretic and antinociceptive activities of Tabernaemontana pandacaqui Poir

J Ethnopharmacol. 2003 Jan;84(1):31-5. doi: 10.1016/s0378-8741(02)00264-7.

Abstract

Studies on carrageenin-induced rat paw edema, yeast-induced hyperthermia in rat and writhing response induced by acetic acid in mice showed that the alcoholic extract of stems of Tabernaemontana pandacaqui (T. pandacaqui) has significant anti-inflammatory, antipyretic and antinociceptive activities. These activities are due to alkaloidal components since they were also observed when the crude alkaloidal (CA) fraction separated from alcoholic extract was tested in the same models.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alkaloids / therapeutic use
  • Analgesics / chemistry
  • Analgesics / therapeutic use
  • Analgesics, Non-Narcotic / chemistry
  • Analgesics, Non-Narcotic / therapeutic use
  • Animals
  • Anti-Inflammatory Agents / chemistry
  • Anti-Inflammatory Agents / therapeutic use
  • Fever / chemically induced
  • Fever / drug therapy*
  • Inflammation / chemically induced
  • Inflammation / drug therapy*
  • Mice
  • Pain / drug therapy*
  • Phytotherapy*
  • Plant Extracts / chemistry
  • Plant Extracts / therapeutic use*
  • Plants, Medicinal / chemistry
  • Rats
  • Rats, Sprague-Dawley
  • Tabernaemontana / chemistry*
  • Thailand

Substances

  • Alkaloids
  • Analgesics
  • Analgesics, Non-Narcotic
  • Anti-Inflammatory Agents
  • Plant Extracts