Detection of hydrogen-bond signature patterns in protein families

Bioinformatics. 2003 Jan;19(1):167-8. doi: 10.1093/bioinformatics/19.1.167.


Summary: We have developed a WWW server, HBPRINT, for the identification of hydrogen-bond signature patterns in protein families from their structures. The server calculates (a) common hydrogen bonds between two structures (b) a hydrogen-bond fingerprint in a set of structural neighbours and (c) details of conserved hydrogen bonds. The server also enables the visualization of the hydrogen bond network comprising the signature pattern.

Availability: HBPRINT and a tutorial are available from

MeSH terms

  • Algorithms
  • Conserved Sequence / genetics*
  • Garlic / chemistry
  • Hydrogen Bonding
  • Internet
  • Plant Lectins / chemistry
  • Plant Lectins / genetics
  • Protein Conformation
  • Proteins / chemistry*
  • Proteins / classification
  • Proteins / genetics
  • Sequence Alignment / methods*
  • Sequence Analysis, Protein / methods
  • User-Computer Interface*


  • Plant Lectins
  • Proteins