Use of oxygenated perfluorocarbon toward making every pancreas count

Transplantation. 2002 Dec 27;74(12):1811-2. doi: 10.1097/00007890-200212270-00032.


The past few years have seen significant advancement in the clinical relevance of intraportal islet cell transplantation for treatment of type 1 diabetes mellitus. The implementation of novel protocols, such as the one developed by the group of Shapiro and collaborators in Edmonton, has revitalized the enthusiasm for cellular transplantation as a treatment for diabetes by improving the success rates and long-term function of islet grafts. Improved results in clinical islet transplantation reported by the groups in Edmonton, Miami, and Minneapolis have re-proposed the much simpler outpatient cell transplant procedure as an alternative to the more risky and technically challenging whole-organ pancreas transplantation.

Publication types

  • Review

MeSH terms

  • Fluorocarbons*
  • Humans
  • Organ Preservation / methods*
  • Oxygen
  • Pancreas Transplantation*


  • Fluorocarbons
  • Oxygen