Six clinical cases of Mandragora autumnalis poisoning: diagnosis and treatment

Eur J Emerg Med. 2002 Dec;9(4):342-7. doi: 10.1097/00063110-200212000-00010.


A multiple case of Mandragora autumnalis poisoning is described. Mandragora autumnalis, a solanaceous plant that is common in the Sicilian countryside, contains a variable concentration of solanum alkaloids, which cause gastrointestinal irritation, and tropane alkaloids, which have anticholinergic properties and produce typical and sometimes severe atropine-like symptoms. Vital function support, decontamination, symptomatic treatment and, in severe cases, antidote therapy with physostigmine are useful to control acute poisoning.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Charcoal / therapeutic use*
  • Female
  • Gastric Lavage
  • Humans
  • Male
  • Mandragora / poisoning*
  • Middle Aged
  • Sicily
  • Treatment Outcome


  • Charcoal