Brosimacutins A-I, nine new flavonoids from Brosimum acutifolium

Junko Takashima; Ayumi Ohsaki

doi:10.1021/np020241f

Brosimacutins A-I, nine new flavonoids from Brosimum acutifolium

J Nat Prod. 2002 Dec;65(12):1843-7. doi: 10.1021/np020241f.

Authors

Junko Takashima¹, Ayumi Ohsaki

Affiliation

¹ Research and Development Division, Mitsubishi Pharma Corporation, Kamoshida-cho, Aoba-ku, Yokohama 227-0033, Japan. Takashima.Junko@me.m-pharma.co.jp

PMID: 12502325
DOI: 10.1021/np020241f

Abstract

Nine new flavonoids, brosimacutins A-I (1-9), and four known flavonoids were isolated from the bark of Brosimum acutifolium, a Brazilian folk medicine ("Mururé"). Their structures were elucidated by spectroscopic methods, including 2D NMR. Brosimacutins A-I possess differentially functionalized isoprene units at C-8.

MeSH terms

Brazil
Flavonoids / chemistry
Flavonoids / isolation & purification*
Medicine, Traditional
Molecular Conformation
Molecular Structure
Moraceae / chemistry*
Nuclear Magnetic Resonance, Biomolecular
Plants, Medicinal / chemistry*
Structure-Activity Relationship

Substances

Flavonoids