An antiplasmodial lignan from Euterpe precatoria

Janne Funder Jensen; Lars Peter Kvist; Søren Brøgger Christensen

doi:10.1021/np020264u

An antiplasmodial lignan from Euterpe precatoria

J Nat Prod. 2002 Dec;65(12):1915-7. doi: 10.1021/np020264u.

Authors

Janne Funder Jensen¹, Lars Peter Kvist, Søren Brøgger Christensen

Affiliation

¹ Department of Medicinal Chemistry, Royal Danish School of Pharmacy, Universitetsparken 2, DK-2100 Copenhagen Ø, Denmark.

PMID: 12502338
DOI: 10.1021/np020264u

Abstract

As a part of a study on new antiplasmodial natural products, a new 8-5' linked lignan dehydrodiconiferyl dibenzoate (2) and p-hydroxybenzoic acid (1) were isolated from the roots of the palm Euterpe precatoria. In contrast to compound 1, compound 2 showed a moderate antiplasmodial activity.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
Antimalarials / chemistry
Antimalarials / isolation & purification*
Antimalarials / pharmacology
Hydroxybenzoates / pharmacology
Lignans / chemistry
Lignans / isolation & purification*
Lignans / pharmacology
Magnoliopsida / chemistry*
Molecular Structure
Peru
Plant Roots
Plants, Medicinal / chemistry*
Plasmodium falciparum / drug effects*

Substances

Antimalarials
Hydroxybenzoates
Lignans
dehydrodiconiferyl dibenzoate