This paper seeks to convey an insight into the interrelationships between body, soul and mind and to show how the concept of "soul" has evolved through the course of history. In German the word "soul" has a confusing array of meanings today. For most of us it comprises all of man's emotions, his awareness, constructive thought, drive, state of mind and spirit. The soul thus represents the essence of a person and his relationships to those closest to him. For many people the soul was and still is the principle of life, the breath of life and the force of life. The immortal soul escapes, leaves the body, is weighed and judged. At all times in history man has doggedly pursued the mysteries of self-awareness, the ultimate truth and the soul. What he found varied, depending on the age and the place. What the Hebrew Bible and the New Testament express in deep-seated metaphors, the Greek philosophers put into clear-cut words: their concept of soul was then largely integrated into Christian thought. Meister Eckhart describes the soul in mystically transfigured passion. C.G. Jung writes of the "animus and anima." Sigmund Freud uses the term "psyche." Radical materialism denies the existence and independence of the soul's processes. The questions where we come from and where we are going, why and what for, no longer find a common answer. Psychiatry, however, takes up the intellectual call of the time and replies to the challenges of the day. Thus, the search for the "soul", a search that occupies so many people, also always involves the search for the whole person.