Validity of the mood disorder questionnaire: a general population study

Am J Psychiatry. 2003 Jan;160(1):178-80. doi: 10.1176/appi.ajp.160.1.178.


Objective: This study tested the validity in the adult general population of the Mood Disorder Questionnaire, a screening instrument for bipolar I and II disorders. The Mood Disorder Questionnaire has been validated in a psychiatric outpatient study group.

Method: A total of 711 subjects (stratified by Mood Disorder Questionnaire score) were randomly selected from a group of 85,358 adult respondents in a nationwide epidemiological general population sample that was balanced for key demographic variables. Of these, 695 subjects received a telephone interview involving an abbreviated version of the Structured Clinical Interview for DSM-IV.

Results: A sensitivity of 0.281 and a specificity of 0.972 were obtained for the Mood Disorder Questionnaire.

Conclusions: The Mood Disorder Questionnaire is a useful screening instrument for bipolar I and II disorders in the community. The operating characteristics of the Mood Disorder Questionnaire in the general population differ substantially from its characteristics in outpatient psychiatric settings.

Publication types

  • Research Support, Non-U.S. Gov't
  • Validation Study

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Bipolar Disorder / diagnosis*
  • Bipolar Disorder / epidemiology
  • Cross-Sectional Studies
  • Female
  • Health Surveys
  • Humans
  • Male
  • Mass Screening* / statistics & numerical data
  • Middle Aged
  • Personality Inventory / statistics & numerical data*
  • Psychometrics
  • Reproducibility of Results
  • United States / epidemiology