Oral tramadol for the treatment of pain of 7-30 days' duration in children

John B Rose; Julia C Finkel; Adriano Arquedas-Mohs; Bruce P Himelstein; Mark Schreiner; Robert A Medve

doi:10.1097/00000539-200301000-00016

Oral tramadol for the treatment of pain of 7-30 days' duration in children

Anesth Analg. 2003 Jan;96(1):78-81, table of contents. doi: 10.1097/00000539-200301000-00016.

Authors

John B Rose¹, Julia C Finkel, Adriano Arquedas-Mohs, Bruce P Himelstein, Mark Schreiner, Robert A Medve

Affiliation

¹ Department of Anesthesiology and Critical Care Medicine, Children's Hospital of Philadelphia, Pennsylvania 19104, USA. rose@email.chop.edu

PMID: 12505927
DOI: 10.1097/00000539-200301000-00016

Abstract

This open-label, multicenter trial was designed to determine the safety profile and analgesic efficacy of tramadol for the treatment of painful conditions lasting 7-30 days in 7-16-yr-old children. We found that tramadol 1-2 mg/kg per os every 4-6 h (maximal dose = 8 mg x kg(-1). d(-1), not to exceed 400 mg/d) is a safe and effective analgesic in this patient population.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Adolescent
Analgesics, Opioid / administration & dosage
Analgesics, Opioid / adverse effects
Analgesics, Opioid / therapeutic use*
Child
Chronic Disease
Female
Humans
Male
Pain / drug therapy*
Pain Measurement
Patient Compliance
Sample Size
Tramadol / administration & dosage
Tramadol / adverse effects
Tramadol / therapeutic use*

Substances

Analgesics, Opioid
Tramadol