Forearm compartment syndrome from intravenous mannitol extravasation during general anesthesia

Anesth Analg. 2003 Jan;96(1):245-6, table of contents. doi: 10.1097/00000539-200301000-00049.


Complications of IV mannitol administration resulting in compartment syndrome may warrant surgical intervention. Compartment syndrome is difficult to diagnose in the anesthetized patient. Infusing mannitol in an observed IV site permits discontinuation of mannitol before complications ensue. Early recognition and surgical intervention averted potential impairment in our patient.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anesthesia, General*
  • Compartment Syndromes / etiology*
  • Compartment Syndromes / physiopathology
  • Diuretics, Osmotic / adverse effects*
  • Edema / etiology
  • Female
  • Forearm / blood supply*
  • Forearm / surgery
  • Humans
  • Intracranial Aneurysm / surgery
  • Mannitol / adverse effects*
  • Middle Aged
  • Regional Blood Flow / drug effects


  • Diuretics, Osmotic
  • Mannitol