Our experience with perfluorohexyloctane (F6H8) as a temporary endotamponade in vitreoretinal surgery

Eur J Ophthalmol. 2002 Nov-Dec;12(6):518-22. doi: 10.1177/112067210201200612.


Purpose: To evaluate the use of F6H8 as a temporary endotamponade for complicated and special cases of retinal detachment instead of silicone oil.

Methods: We have used F6H8 with 14 patients since February 1999. Eight suffered from rhegmatogenous retinal detachment (RRD) with multiple tears located inferiorly. Three presented inferior traction retinal detachment (TRD) under silicone oil, two suffered from ocular trauma with inferior TRD, and one had idiopathic macular hole. The substance was introduced into the eye after pars plana vitrectomy and membrane peeling if needed, and we tried to introduce as much as possible.

Results: With F6H8 the retina was easily reattached in all cases, like with perfluorocarbon liquids. The postoperative view was very good. F6H8 was removed in all cases after 3-8 weeks. Anatomical success was achieved in 12 out of 14 eyes. Two eyes presented severe PVR. F6H8 entered the anterior chamber in 4 cases, but no corneal complications occurred. In one case there was a marked IOP rise due to an anterior block, treated with superior iridotomy. In two cases retinal detachment (RD) occurred in the upper part and was treated with additional surgery, F6H8 removal and silicone oil injection.

Conclusions: F6H8 seems to be a promising tamponade agent for special cases of RD.

Publication types

  • Clinical Trial

MeSH terms

  • Aged
  • Epiretinal Membrane / surgery
  • Female
  • Fluorocarbons / therapeutic use*
  • Humans
  • Intraocular Pressure
  • Male
  • Middle Aged
  • Retinal Detachment / drug therapy*
  • Retinal Perforations / drug therapy*
  • Treatment Outcome
  • Visual Acuity
  • Vitrectomy


  • Fluorocarbons
  • perfluorohexyl-octan