Primary low-grade B-cell lymphoma of the urinary bladder: case report and literature review

Can J Urol. 2002 Dec;9(6):1694-7.


The first recorded case of lymphoma of the bladder was reported by Eve and Chaffey in 1885. Malignant lymphoma of the bladder can be classified into one of three different clinical groups: 1) Primary lymphoma localized to the bladder; 2) Lymphoma presenting in the bladder as the first sign of disseminated disease (non-localized lymphoma); 3) Recurrent bladder involvement by lymphoma in patients with a history of malignant lymphoma (secondary lymphoma). Primary extranodal marginal zone lymphoma of mucosa associated lymphoid tissue (MALT type) of the urinary bladder, first described by Kempton et al in 1990, is the most common primary bladder lymphoma and associated with an excellent prognosis. We present a patient with gross hematuria who was found to have a primary bladder lymphoma and review the relevant literature.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Combined Modality Therapy
  • Female
  • Hematuria / etiology
  • Humans
  • Lymphoma, B-Cell, Marginal Zone* / diagnosis
  • Lymphoma, B-Cell, Marginal Zone* / radiotherapy
  • Lymphoma, B-Cell, Marginal Zone* / surgery
  • Middle Aged
  • Urinary Bladder Neoplasms* / diagnosis
  • Urinary Bladder Neoplasms* / radiotherapy*
  • Urinary Bladder Neoplasms* / surgery