Postmalaria neurological syndrome: two cases from the Gambia

Clin Infect Dis. 2003 Jan 15;36(2):e29-31. doi: 10.1086/344774. Epub 2002 Dec 31.


We describe 2 patients with severe Plasmodium falciparum malaria whose convalescence was complicated by fever, with acute confusion and acalculia in one patient and a triad of myoclonus, tremor, and dysphasia in the other. Inflammatory changes were found in cerebrospinal fluid samples. Postmalaria neurological syndrome was diagnosed in each patient, and a therapeutic response to oral corticosteroids was seen in the second patient.

Publication types

  • Case Reports

MeSH terms

  • Adrenal Cortex Hormones / therapeutic use
  • Adult
  • Animals
  • Female
  • Gambia
  • Humans
  • Malaria / complications*
  • Malaria / parasitology
  • Male
  • Nervous System Diseases / drug therapy
  • Nervous System Diseases / etiology*
  • Plasmodium falciparum
  • Syndrome


  • Adrenal Cortex Hormones