ELF fields and photooxidation yielding lethal effects on cancer cells

Bioelectromagnetics. 2003 Feb;24(2):148-50. doi: 10.1002/bem.10082.

Abstract

The lethal effect on human cancer cells was studied under three types of treatment: A) an ELF pulsed sinusoidal of 50 Hz electromagnetic field (PEMF) with amplitudes between 10 and 55 mT; B) the field and a cytostatic agent (actinomycin-C); and C) the field, the cytostatic agent, which has a photodynamic effect, and exposure to a halogen lamp. The results show a decreasing vitality of human K-562 and U-937 cancer cells in suspension with each additional treatment. Combination with other parameters as hyperthermia and/or hyperacidity could yield high killing rates by this noninvasive method.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Apoptosis / drug effects
  • Apoptosis / radiation effects
  • Dactinomycin / analogs & derivatives*
  • Dactinomycin / pharmacology*
  • Electromagnetic Fields
  • Humans
  • K562 Cells / drug effects*
  • K562 Cells / radiation effects*
  • Light
  • Photochemotherapy / methods
  • U937 Cells / drug effects*
  • U937 Cells / radiation effects*

Substances

  • cactinomycin
  • Dactinomycin