P(i-BuNCH2CH2)3N: an effective ligand in the palladium-catalyzed amination of aryl bromides and iodides

Sameer Urgaonkar; M Nagarajan; J G Verkade

doi:10.1021/jo0205309

P(i-BuNCH2CH2)3N: an effective ligand in the palladium-catalyzed amination of aryl bromides and iodides

J Org Chem. 2003 Jan 24;68(2):452-9. doi: 10.1021/jo0205309.

Authors

Sameer Urgaonkar¹, M Nagarajan, J G Verkade

Affiliation

¹ Department of Chemistry, Gilman Hall, Iowa State University, Ames 50011, USA.

PMID: 12530871
DOI: 10.1021/jo0205309

Abstract

It is shown that the bicyclic triaminophosphine P(i-BuNCH2CH2)3N serves as an effective ligand for the palladium-catalyzed amination of a wide array of aryl bromides and iodides. Other bicyclic or acyclic triaminophosphines, even those of similar basicity and/or bulk, were inferior.