Atopic dermatitis

Lancet. 2003 Jan 11;361(9352):151-60. doi: 10.1016/S0140-6736(03)12193-9.


Atopic dermatitis is a highly pruritic chronic inflammatory skin disorder affecting 10-20% of children worldwide. Symptoms can persist or begin in adulthood. It is also the most common cause of occupational skin disease in adults. This disease results from an interaction between susceptibility genes, the host's environment, pharmacological abnormalities, skin barrier defects, and immunological factors. New management approaches have evolved from advances in our understanding of the pathobiology of this common skin disorder.

Publication types

  • Review

MeSH terms

  • Administration, Topical
  • Adult
  • Anti-Bacterial Agents / therapeutic use*
  • Anti-Inflammatory Agents / therapeutic use*
  • Child
  • Dermatitis, Atopic* / diagnosis
  • Dermatitis, Atopic* / drug therapy
  • Dermatitis, Atopic* / physiopathology
  • Diagnosis, Differential
  • Food Hypersensitivity
  • Glucocorticoids
  • Humans
  • Prevalence


  • Anti-Bacterial Agents
  • Anti-Inflammatory Agents
  • Glucocorticoids