Fusion and fission events in the endocytic pathway of Dictyostelium

Traffic. 2003 Jan;4(1):1-5. doi: 10.1034/j.1600-0854.2003.40101.x.


The endocytic pathway in Dictyostelium appears as a short circuit between endocytosis and exocytosis. Within the hour that elapses between internalization of nutrients and release of remnants, digestion by lysosomal enzymes occurs. Meanwhile, the maturing endosome undergoes a complex series of fusion and fission events, which change its character profoundly and which are far from being fully understood. This review attempts to order the dynamic events into a sequence of stages that is most consistent with present knowledge.

Publication types

  • Review

MeSH terms

  • Animals
  • Dictyostelium / cytology
  • Dictyostelium / physiology*
  • Endocytosis / physiology*
  • Endosomes / physiology