[The influence of coffee and caffeine on gastrin and acid secretion in man (author's transl)]

Dtsch Med Wochenschr. 1976 Mar 19;101(12):455-7.
[Article in German]


Intragastric instillation of coffee, decaffeinated coffee and pure caffeine in humans significantly stimulated gastric secretion. After intragastric caffeine, basal serum gastrin concentrations were not changed. However after instillation of coffee and decaffeinated coffee serum gastrin increased significantly. Thus acid secretion was significantly greater after coffee and decaffeinated coffee than after caffeine. Roasted products seem to be responsible for the gastrin-releasing effect of coffee.

Publication types

  • English Abstract

MeSH terms

  • Caffeine / pharmacology*
  • Coffee*
  • Gastric Acidity Determination
  • Gastric Mucosa / drug effects*
  • Gastrins / blood*
  • Humans
  • Time Factors


  • Coffee
  • Gastrins
  • Caffeine