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, 13 (12), 801-4

Urinary Tract Infection in Patients With Acute Non-Gonococcal Urethritis


Urinary Tract Infection in Patients With Acute Non-Gonococcal Urethritis

Andrew Leung et al. Int J STD AIDS.


In young sexually active male patients, clinical differentiation between non-gonococcal urethritis (NGU) and urinary tract infection (UTI) can be difficult. UTI as a cause of NGU has been suggested before, but the prevalence of UTI among acute NGU patients has not been evaluated. We conducted a prospective cross-sectional study of 156 male patients with clinical features of acute urethritis. The prevalence of UTI among acute NGU patients was 6.4% (CI: 1.5-11.3%). There was a possible association between UTI and NGU but this was not statistically significant. The sensitivity and specificity for combining leucocyte esterase and nitrite tests were 83.3% and 89.8%, respectively, with a negative predictive value of 98.8%. We conclude that a mid-stream urine specimen should routinely be collected in patients with symptoms of urethritis. This should be analysed by dipsticks incorporating nitrite and leucocyte esterase tests. Those with a positive dipstick should then be confirmed by culture.

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Cited by 2 PubMed Central articles

  • Management of Non-Gonococcal Urethritis
    H Moi et al. BMC Infect Dis 15, 294. PMID 26220178. - Review
    Non-gonococcal urethritis (NGU), or inflammation of the urethra, is the most common treatable sexually transmitted syndrome in men, with approximately 20-50 % of cases be …
  • Asymptomatic Men: Should They Be Tested for Urethritis?
    P Horner. Sex Transm Infect 83 (2), 81-4. PMID 17435050.
    More research is needed to determine the cost effectiveness of testing for urethritis

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