Partial Splenectomy in Cystic Fibrosis Patients With Hypersplenism

Arch Dis Child. 2003 Feb;88(2):143-6. doi: 10.1136/adc.88.2.143.

Abstract

We report three cystic fibrosis (CF) patients with hypersplenism who underwent partial splenectomy. The postoperative course was uneventful in two patients; one patient developed a complication necessitating resection of the rest of the spleen. Haematological parameters improved and oesophageal varices regressed in all patients. On follow up, one patient showed a normal spleen, the other a normally functioning accessory spleen; the third patient again developed splenomegaly with hypersplenism. Partial splenectomy is a promising therapeutic option for CF patients with hypersplenism.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Adult
  • Cystic Fibrosis / complications
  • Cystic Fibrosis / surgery*
  • Female
  • Humans
  • Hypersplenism / complications
  • Hypersplenism / surgery*
  • Male
  • Spleen / surgery
  • Splenectomy / methods*