[Treatment of hemangioma in oral and maxillofacial region with pingyangmycin injection]

Hua Xi Kou Qiang Yi Xue Za Zhi. 2000 Oct;18(5):317-9.
[Article in Chinese]


Objective: To investigate the indication and result in hemangioma in oral and maxillofacial region with Pingyangmycin injection.

Methods: 1282 patients (554 males and 728 females) with hemangioma in oral and maxillofacial region have been treated in our hospital during the 10-year period from May 1990 to March 1999. The patients range between 0.5-84 years old. Lip, cheek and tongue were usually involved. 1211 patients were treated with injection of Pingyangmycin(about 0.89 mg/ml) and dexamethasone (about 0.55 mg/ml), 1 time/1-2 weeks.

Results: The curative rates of cavernous hemangioma and strawberry hemangioma were 93.87% and 84.90%, but that of plexiform hemangioma was 22.22% and those of portwine stain and central hemangioma of the jaws were 0%, respectively. Serious complications associated with Pingyangmycin injection, such as pulmonary fibrosis were not seen.

Conclusion: Injection of Pingyangmycin is selective primary method for cavernous and strawberry hemangioma treatment.

Publication types

  • English Abstract

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Antibiotics, Antineoplastic / administration & dosage*
  • Antibiotics, Antineoplastic / therapeutic use
  • Bleomycin / administration & dosage*
  • Bleomycin / analogs & derivatives*
  • Child
  • Child, Preschool
  • Facial Neoplasms / drug therapy*
  • Female
  • Hemangioma, Cavernous / drug therapy*
  • Hemangioma, Cavernous / pathology
  • Humans
  • Infant
  • Infant, Newborn
  • Injections, Intralesional
  • Jaw Neoplasms / drug therapy
  • Male
  • Middle Aged
  • Mouth Neoplasms / drug therapy*


  • Antibiotics, Antineoplastic
  • Bleomycin
  • zhengguangmycin