The genomics of insecticide resistance

Genome Biol. 2003;4(1):202. doi: 10.1186/gb-2003-4-1-202. Epub 2003 Jan 3.


Genomic technologies are revealing several mechanisms of insecticide resistance involving enhanced detoxification or reduced target-site sensitivity that had previously defied molecular analyses. Genome projects are also revealing some potentially far-reaching consequences for pest-insect genomes of the rapid accumulation of multiple resistance mutations in very short periods of evolutionary time.

Publication types

  • Review

MeSH terms

  • Animals
  • Cytochrome P-450 Enzyme System / genetics
  • Evolution, Molecular
  • Genomics*
  • Insecta / enzymology
  • Insecta / genetics
  • Insecticide Resistance / genetics*
  • Mutation
  • Quantitative Trait Loci / genetics


  • Cytochrome P-450 Enzyme System