Snf1 protein kinase: a key player in the response to cellular stress in yeast

Biochem Soc Trans. 2003 Feb;31(Pt 1):178-81. doi: 10.1042/bst0310178.

Abstract

Sucrose non-fermenting 1 (Snf1) protein kinase, a yeast homologue of mammalian AMP-activated protein kinase, plays a main role in transcriptional activation and repression of gene expression. In addition, Snf1 kinase has a broad role in the cellular response to several forms of stress, such as nutrient limitation, salt stress and heat shock.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Gene Expression Regulation, Fungal
  • Glycogen / metabolism
  • Hot Temperature
  • Lipid Metabolism
  • Models, Biological
  • Protein-Serine-Threonine Kinases / physiology*
  • Saccharomyces cerevisiae / physiology*
  • Salts / pharmacology
  • Transcriptional Activation

Substances

  • Salts
  • Glycogen
  • SNF1-related protein kinases
  • Protein-Serine-Threonine Kinases