Preparation and properties of a national reference endotoxin

J Clin Microbiol. 1976 Jan;3(1):21-5.


A large pool of refined endotoxin was prepared from Escherichia coli O113 by extraction with hot acqueous phenol. It was characterized chemically and biologically and will be available for a reference standard designated as reference endotoxin EC.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Animals
  • Chick Embryo
  • Hot Temperature
  • Phenols
  • Rabbits


  • Phenols