Trace amine receptors as targets for novel therapeutics: legend, myth and fact

Curr Opin Pharmacol. 2003 Feb;3(1):90-7. doi: 10.1016/s1471-4892(02)00028-0.


Trace amines are attracting attention as neurotransmitters because they are believed to play a role in human disorders such as schizophrenia, depression, attention deficit disorder and Parkinson's disease. Research to date is promising and confirms the need for continuing work to forge the way for new drug discovery.

Publication types

  • Review

MeSH terms

  • Animals
  • Biogenic Amines / agonists
  • Biogenic Amines / antagonists & inhibitors
  • Biogenic Amines / therapeutic use*
  • Drug Delivery Systems / methods*
  • Humans
  • Mental Disorders / drug therapy
  • Mental Disorders / metabolism
  • Nervous System Diseases / drug therapy
  • Nervous System Diseases / metabolism
  • Receptors, Cell Surface / agonists
  • Receptors, Cell Surface / antagonists & inhibitors
  • Receptors, Cell Surface / therapeutic use*


  • Biogenic Amines
  • Receptors, Cell Surface