The pre-ribosomal network

Nucleic Acids Res. 2003 Feb 1;31(3):799-804. doi: 10.1093/nar/gkg165.


Recent achievements in yeast functional proteomics have significantly advanced our knowledge about ribosome biogenesis. Here, we present a program developed to integrate data from various proteome analyses with cell biological data on components present in the ribosome producing factories. This program allows users to attribute factors to certain complexes and to specific steps of ribosome biogenesis. Thus, it helps to gain novel insights into the complex network involved in maturation of ribosomal subunits. The database can be accessed at the URL

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Biomarkers / analysis
  • Macromolecular Substances
  • Models, Molecular
  • Proteome / analysis
  • Ribosomal Proteins / analysis*
  • Ribosomal Proteins / classification
  • Ribosomes / chemistry
  • Ribosomes / metabolism*
  • Yeasts / metabolism*


  • Biomarkers
  • Macromolecular Substances
  • Proteome
  • Ribosomal Proteins