Infectious disease hospitalizations among American Indian and Alaska native infants

Pediatrics. 2003 Feb;111(2):E176-82. doi: 10.1542/peds.111.2.e176.


Objective: To describe the burden and trends in hospitalizations associated with infectious diseases among American Indian and Alaska Native (AI/AN) infants.

Methods: First-listed infectious disease hospitalizations and hospitalization rates among AI/AN infants and infants in the general US population from 1988-1999 were analyzed by using Indian Health Service/tribal hospital discharge data and the National Hospital Discharge Survey data, respectively.

Results: Infectious disease hospitalizations accounted for 53% of all AI/AN infant hospitalizations and approximately 43% of all US infant hospitalizations during 1988-1999. The annual hospitalization rate for infectious diseases among AI/AN infants declined from 27,486 per 100,000 infants in 1988 to 14,178 per 100,000 infants in 1999. However, the rates for AI/AN infants within the Alaska, Southwest, and Northern Plains regions remained higher than that for the general US infant population at the end of the study period. Lower respiratory tract infection hospitalizations accounted for almost 75% of AI/AN infant infectious disease hospitalizations, and the lower respiratory tract infection hospitalization rate for AI/AN infants was twice that for US infants.

Conclusions: Although infectious disease hospitalization rates for AI/AN infants have declined, AI/AN infants continue to have a higher infectious disease burden than the general US infant population.

Publication types

  • Comparative Study
  • Multicenter Study

MeSH terms

  • Age Factors
  • Alaska / epidemiology
  • Child, Hospitalized / statistics & numerical data*
  • Communicable Diseases / epidemiology*
  • Communicable Diseases / mortality
  • Databases, Factual / statistics & numerical data
  • Female
  • Health Care Surveys / statistics & numerical data
  • Hospital Mortality / trends
  • Humans
  • Indians, North American / statistics & numerical data*
  • Infant
  • Infant, Newborn
  • Inuit / statistics & numerical data
  • Length of Stay / statistics & numerical data
  • Length of Stay / trends
  • Male
  • Mortality / trends
  • Sex Factors
  • United States / epidemiology
  • United States Indian Health Service / statistics & numerical data