Caveolae--from ultrastructure to molecular mechanisms

Nat Rev Mol Cell Biol. 2003 Feb;4(2):162-7. doi: 10.1038/nrm1017.


Almost 50 years after the first sighting of small pits that covered the surface of mammalian cells, investigators are now getting to grips with the detailed workings of these enigmatic structures that we now know as caveolae.

Publication types

  • Historical Article
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Biological Transport
  • Caveolae / physiology
  • Caveolae / ultrastructure*
  • Caveolins / physiology
  • History, 20th Century
  • Humans
  • Mice
  • Mice, Knockout
  • Signal Transduction / physiology


  • Caveolins