Emerging technologies in screening for colorectal cancer: CT colonography, immunochemical fecal occult blood tests, and stool screening using molecular markers

CA Cancer J Clin. Jan-Feb 2003;53(1):44-55. doi: 10.3322/canjclin.53.1.44.


The American Cancer Society's (ACS) Colorectal Cancer Advisory Group held a workshop on new technologies for the early detection of colorectal cancer and adenomatous polyps as part of a regular review of ACS guidelines for colorectal cancer screening. The Advisory Group formally reviewed CT colonography, immunochemical fecal occult blood tests (FOBT), and stool screening using molecular markers, and also addressed other technologies including capsule video endoscopy. With the exception of immunochemical stool testing, the ACS has determined that at this time there is insufficient evidence to recommend these technologies for routine colorectal cancer screening. Based on recommendations of the Advisory Group, only a minor modification has been made to the ACS's Recommendations for Screening and Surveillance of the Early Detection of Adenomatous Polyps and Colorectal Cancer.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Adenomatous Polyps / diagnosis*
  • Aged
  • American Cancer Society
  • Biomarkers / analysis
  • Colonography, Computed Tomographic
  • Colorectal Neoplasms / diagnosis*
  • DNA Mutational Analysis / methods
  • Endoscopy, Gastrointestinal / methods
  • Evidence-Based Medicine
  • Female
  • Humans
  • Immunochemistry / methods
  • Male
  • Mass Screening / trends*
  • Middle Aged
  • Occult Blood


  • Biomarkers