Cholesterol vehicle in experimental atherosclerosis 24: avocado oil

J Am Coll Nutr. 2003 Feb;22(1):52-5. doi: 10.1080/07315724.2003.10719275.


Objective: To determine atherogenicity of avocado oil relative to saturated (coconut oil), monounsaturated (olive oil) and polyunsaturated (corn oil) fats.

Methods: New Zealand White rabbits were fed a semipurified diet containing 0.2% cholesterol and 14% fat for 90 days. They were then necropsied and severity of atherosclerosis was determined visually.

Results: Coconut oil was the most atherogenic fat. Corn oil was only slightly less atherogenic than either olive or avocado oils. Percentage of serum HDL cholesterol was highest in the rabbits fed the two monounsaturated fats.

Conclusion: Avocado oil is of the same order of atherogenicity as corn oil and olive oil.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Arteriosclerosis / etiology*
  • Arteriosclerosis / pathology
  • Cholesterol / blood
  • Coconut Oil
  • Corn Oil
  • Diet, Atherogenic*
  • Disease Models, Animal
  • Fatty Acids, Monounsaturated / administration & dosage
  • Fatty Acids, Unsaturated / administration & dosage
  • Male
  • Persea*
  • Plant Oils / administration & dosage*
  • Rabbits
  • Random Allocation
  • Severity of Illness Index


  • Fatty Acids, Monounsaturated
  • Fatty Acids, Unsaturated
  • Plant Oils
  • Corn Oil
  • Cholesterol
  • Coconut Oil