Emergence of an IMP-like Metallo-Enzyme in an Acinetobacter Baumannii Clinical Strain From a Brazilian Teaching Hospital

Diagn Microbiol Infect Dis. 2003 Jan;45(1):77-9. doi: 10.1016/s0732-8893(02)00500-x.

Abstract

Multidrug-resistant Acinetobacter spp. constitute a serious cause of nosocomial infection in Brazilian hospitals. This manuscript reports the first appearance of an IMP-like metallo-beta-lactamase encountered in a clinical isolate of A. baumannii from a Brazilian teaching hospital.

MeSH terms

  • Acinetobacter Infections / drug therapy
  • Acinetobacter Infections / epidemiology
  • Acinetobacter baumannii / drug effects*
  • Acinetobacter baumannii / enzymology*
  • Anti-Bacterial Agents / pharmacology
  • Base Sequence
  • Brazil / epidemiology
  • Cross Infection / epidemiology
  • Cross Infection / microbiology
  • DNA, Bacterial / analysis
  • Drug Resistance, Multiple*
  • Hospitals, Teaching
  • Humans
  • Male
  • Microbial Sensitivity Tests
  • Molecular Sequence Data
  • Polymerase Chain Reaction
  • Sensitivity and Specificity
  • beta-Lactamases / drug effects*
  • beta-Lactamases / metabolism

Substances

  • Anti-Bacterial Agents
  • DNA, Bacterial
  • beta-lactamase IMP-1
  • beta-Lactamases