Clinical utility of urinary antigen detection for diagnosis of community-acquired, travel-associated, and nosocomial legionnaires' disease

J Clin Microbiol. 2003 Feb;41(2):838-40. doi: 10.1128/jcm.41.2.838-840.2003.


The clinical utility of Legionella urinary antigen assays for the diagnosis of Legionnaires' disease was assessed by using samples from 317 culture-proven cases. The sensitivities of the Binax enzyme immunoassay (EIA) and Biotest EIA were found to be 93.7 and 94.4% for travel-associated infection and 86.5 and 76.0% for community-acquired infection but only 44.2 and 45.7% for nosocomially acquired infection, respectively.

MeSH terms

  • Antigens, Bacterial / urine*
  • Community-Acquired Infections / diagnosis*
  • Cross Infection / diagnosis*
  • Humans
  • Immunoenzyme Techniques
  • Legionnaires' Disease / diagnosis*
  • Sensitivity and Specificity
  • Travel


  • Antigens, Bacterial