Adhesive arachnoiditis after lumbar radiculography with Dimer-X and Depo-Medrol

Radiology. 1976 Apr;119(1):153-5. doi: 10.1148/119.1.153.


Lumbar radiculographs were obtained in 252 patients with suspected disk herniation. Fifteen patients who underwent previous radiculography with Dimer-X plus Depo-Medrol exhibited adhesive arachnoiditis. This was not observed in 6 patients who received Dimer-X alone. No positive correlation between radiological diagnosis of adhesive arachnoiditis and clinical symptoms can be demonstrated. The authors suggest that steroids not be used intrathecally in combination with water-soluble contrast media.

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Arachnoiditis / chemically induced*
  • Humans
  • Intervertebral Disc Displacement / diagnostic imaging
  • Intervertebral Disc Displacement / surgery
  • Iothalamate Meglumine / adverse effects*
  • Iothalamic Acid / analogs & derivatives*
  • Methylprednisolone / adverse effects*
  • Middle Aged
  • Myelography / methods*
  • Sciatica


  • Iothalamic Acid
  • Methylprednisolone
  • Iothalamate Meglumine