Abstract
Iochimbin hydrochloride was given to 153 men with erectile dysfunction. The results are available for 140 of them. The ability of iochimbin in a single dose of 5-10 mg to enhance arterial blood inflow to cavernous bodies of the penis was confirmed by dynamic angiopenoscintigraphy and Doppler ultrasonography. Iochimbin hydrochloride in a mean daily dose of 15-20 mg proved effective in erectile dysfunction--38 to 84% responders depending on the type of erectile dysfunction. Occasional side effects can be relieved by reducing the drug dose.
MeSH terms
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Administration, Oral
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Adrenergic alpha-Antagonists / administration & dosage
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Adrenergic alpha-Antagonists / adverse effects
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Adrenergic alpha-Antagonists / therapeutic use*
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Adult
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Aged
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Erectile Dysfunction / diagnostic imaging
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Erectile Dysfunction / drug therapy*
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Erectile Dysfunction / etiology
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Erectile Dysfunction / psychology
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Humans
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Male
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Middle Aged
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Penis / blood supply
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Penis / diagnostic imaging
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Radionuclide Imaging
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Risk Factors
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Ultrasonography, Doppler
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Yohimbine / administration & dosage
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Yohimbine / adverse effects
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Yohimbine / therapeutic use*
Substances
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Adrenergic alpha-Antagonists
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Yohimbine