Role of the fastigial nucleus in controlling horizontal saccades during adaptation

Ann N Y Acad Sci. 2002 Dec;978:63-78. doi: 10.1111/j.1749-6632.2002.tb07556.x.


Saccade size was adapted in rhesus monkeys using surgical weakening of the muscles of one eye combined with monocular viewing. Neurons in the caudal fastigial nucleus were recorded during the adaptation. Neuronal discharges changed in a way that could be interpreted as causing the changes in saccade size given our current knowledge of the projections of these neurons to the saccadic burst generator in the brain stem.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adaptation, Physiological / physiology*
  • Animals
  • Cerebellar Nuclei / physiology*
  • Macaca mulatta
  • Neuronal Plasticity / physiology
  • Nystagmus, Pathologic / physiopathology
  • Saccades / physiology*