[Does a reduced kidney function (creatinine clearance 10-15 ml/min), without acidosis, increase the risk for the rise of lactic acidosis caused by metformin?]

MeSH terms

• Acidosis, Lactic / chemically induced
• Acidosis, Lactic / etiology*
• Acidosis, Lactic / mortality
• Contraindications
• Diabetes Mellitus, Type 2 / drug therapy
• Diabetic Ketoacidosis / chemically induced
• Diabetic Ketoacidosis / etiology
• Diabetic Ketoacidosis / mortality
• Diabetic Nephropathies / complications*
• Humans
• Hypoglycemic Agents / adverse effects*
• Metformin / adverse effects*
• Renal Insufficiency / complications*