Abstract
In asthmatic children with persistent symptoms, maintenance therapy with nedocromil sodium, inhaled corticosteroids, or montelukast is associated with a decreased rate of asthma exacerbations. The greatest benefit is seen with use of regular inhaled corticosteroids in preschool- or school-age children, in whom asthma exacerbations, the need for rescue oral corticosteroids, unscheduled urgent medical visits, and hospitalizations are all decreased by approximately 50%. However, maintenance therapy is not beneficial in children with intermittent respiratory virus-induced wheezing without persistent symptoms.
MeSH terms
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Acute Disease
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Administration, Inhalation
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Adrenal Cortex Hormones / therapeutic use
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Adrenergic beta-Agonists / therapeutic use*
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Anti-Asthmatic Agents / therapeutic use*
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Asthma / drug therapy*
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Asthma / virology*
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Child
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Common Cold / complications
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Common Cold / drug therapy
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Common Cold / virology
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Glucocorticoids / therapeutic use*
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Humans
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Leukotriene Antagonists / therapeutic use*
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Respiratory Sounds
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Respiratory Tract Infections / complications*
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Respiratory Tract Infections / virology*
Substances
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Adrenal Cortex Hormones
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Adrenergic beta-Agonists
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Anti-Asthmatic Agents
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Glucocorticoids
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Leukotriene Antagonists