A structural view of integrin activation and signaling

Dev Cell. 2003 Feb;4(2):149-51. doi: 10.1016/s1534-5807(03)00034-0.


Integrins connect the matrix to the cytoskeleton and propagate structural order between the two systems. A series of elegant structural papers now provides a compelling explanation of how integrins perform this basic function.

Publication types

  • Review

MeSH terms

  • Cell Adhesion
  • Cytoskeleton / metabolism
  • Extracellular Matrix / metabolism
  • Humans
  • Integrins / physiology*
  • Signal Transduction / physiology*


  • Integrins